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Some drugs administered this way are intended to have a local effect, for example to treat oral or throat infections.
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The three ways by which substances, including drugs, can cross cell membranes are simple diffusion, facilitated diffusion and active transport.
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In these situations, drugs least likely to harm the foetus should be used.
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Certain drugs are excreted via expiration; the rate of excretion depends on plasma concentration, alveolar air concentration and blood-gas partition.
According to the protein theory, the site of action is a hydrophobic region of cellular proteins, possibly receptors or proteins involved in transmitter release. Interaction with general anaesthetic would result in reduction in the excitability of the cell and inhibition of nerve transmission.
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This prevents the formation of certain prostaglandins that would otherwise cause inflammation and pain. Other drugs act as false substrates for the enzyme so that an abnormal product is made instead of the normal one.
Given that prescribing can be considered to include advising a patient on suitable care or medication including over-the-counter drugs as well as the more familiar written orders or prescriptions, there is considerable scope for health care professionals to be involved in patient medication. There are in fact five ways in which suitably qualified and registered health care professionals can supply medicines to patients: patient group directions, patient specific directions (PSDs), supplementary prescribing, independent prescribing and specific exemptions to the Medicines Act.
The first three of these require a working partnership with medically qualified professionals; the last two do not. Two sections presented here have been written by practitioners in podiatry and radiography. In addition, practitioners in podiatry and physiotherapy have made verbal contributions to this chapter. Collectively they have described the use of various forms of access, supply, administration and prescription of medicines in their professions today and considered future developments in the light of the recent legislation allowing pharmacists and nurses to train as independent prescribers.

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Drug therapy is not the only possibility. Psychotherapy therapy techniques such as relaxation, cognitive behavioural therapy and counselling can benefit some patients. Drug therapy of anxiety is mainly with a group of drugs called benzodiazepines.