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In conversation, he tells you that he has depression and is currently going through a particularly bad patch that has lasted several months.
The abnormal brain activity involves the whole of the cerebral cortex. Seizures last for several minutes and may be preceded by an вauraв, which is a kind of warning that an attack is about to happen. Status epilepticus is a series of seizures without recovery of consciousness in between. Absence seizures are brief periods of loss of consciousness with little motor activity, maybe just eyelid blinking or muscle jerking.
All are thought to improve negative as well as positive symptoms of schizophrenia in addition to causing fewer motor side effects and are less likely to affect prolactin secretion. Examples of atypical anti-psychotic drugs are clozapine, risperidone, olanzapine and quetiapine. Clozapine can cause agranulocytosis and should only be used if other drugs are not effective. Other adverse effects of most anti-psychotic drugs are anti-cholinergic effects such as dry mouth, constipation and urinary retention and О-adrenergic blocking effects, primarily vasodilation leading to a fall in blood pressure especially in the elderly.
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Pathological features of Alzheimerвs disease are extracellular plaques of О-amyloid protein and neurofibrillary tangles. О-amyloid plaques are found particularly in the hippocampus and association areas of the cerebral cortex. Similar plaques are seen in unaffected individuals, but there are many more in patients with Alzheimerвs disease.
Their formation may be due to abnormal metabolism of a precursor protein. Neurofibrillary tangles are found in neurons and may be collections of abnormal microtubule proteins, which form as a result of cell destruction.
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Resistance to antimalarial drugs is now common. The most severe form of malaria is caused by Plasmodium falciparum and can be fatal. Fever occurs every third day due to rupture of infected red blood cells. Other forms are less severe and rarely fatal.
References Department of Health Review of Prescribing, Supply and Administration of Medicines, Department of Health London. http:www. gov. ukenPolicyAndGuidanceMedicinesPharmacyAndIndustry PrescriptionsTheNon-MedicalPrescribingProgrammeindex. htm Department of Health Non-medical Prescribing.
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