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Life will continue on the Open farm as all our animals still need feeding, cleaning out and looking after. Not to mention all the gorgeous lambs that still need bottle feeding and that are due to be born. We wish you and your families all the best and we will see you all soon. You can come and enjoy breakfast, lunch, an early supper or anything in between. For those who've worked up an appetite, we have everything from homemade pizzas to country soups and gourmet ciabattas. Both kids and adult meals are served daily in our PlayBarn.
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Hypersecretion of cortisol (Cushingвs syndrome) and testosterone are managed with surgery or irradiation.
Systemic fungal infections have become more common due to overuse of antibiotics and increase in numbers of immunocompromized patients. Many antifungal drugs work by interfering with ergosterol production thus making the fungal cell membrane leaky.
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The main adverse effect of carbimazole is granulocytopenia; this is rare and reversible on stopping drug therapy. Radioactive iodine is also used to treat thyrotoxicosis and to assess thyroid function. Eventually it causes hypothyroidism, which has to be treated by thyroid hormone replacement. Hyposecretion of thyroid hormone due to absence or incomplete development of the thyroid in early life causes cretinism, which is characterized by stunted growth and mental deficiency.
Hyposecretion in adults results in myxoedema, a condition where there is a characteristic thickening of the skin together with low metabolic rate, slow speech, poor appetite, weight gain, lethargy, bradycardia, sensitivity to cold and mental impairment. One form is Hashimotoвs thyroiditis, an autoimmune condition where antibodies are produced against thyroglobulin.
The phases of a cardiac action potential are shown in Figure change in resting membrane potential of cardiac muscle cells from в This is due to influx of sodium ions followed by influx of calcium ions. Contraction of the myocardium follows depolarization. The refractory period is the time interval when a second contraction cannot occur and repolarization is the recovery of the resting potential due to efflux of potassium ions.
After this the cycle repeats itself. A typical ECG is shown in Figure and contraction; the QRST complex corresponds to atrial repolarization and relaxation and the onset of ventricular depolarization and contraction; and the T wave represents ventricular repolarization and relaxation.