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In accordance with national advice, the survey revealed that more than half of them had been trained in-house while the remainder had attended a university-based post-registration programme.
Adverse reactions can occur with any drug use and can be either related to or unrelated to the expected pharmacological effect. Variation in effect of a drug can occur in different individuals and indeed in the same individuals on different occasions. This can result from either differing concentrations of a drug at its site of action, or differing physiological responses to the same concentration of a drug. Adverse drug reactions present a major clinical problem.
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Increase in increments of mg weekly to a maximum of 2, mg daily in divided doses. Adjust dosages of both drugs until glycemic control adequate. If response inadequate within 1 to 3 months of concurrent therapy, consider alternatives. Individualize dosage adjustments based on glycemic response. Stop drug if acidosis occurs. Advise him to take it with meals to reduce these effects, and tell him that adverse effects often subside over time.
These may warrant dosage decrease or drug withdrawal. Action Increases insulin sensitivity by decreasing glucose production and absorption in liver and intestines and enhancing glucose uptake and utilization. Adverse reactions GI: diarrhea, nausea, vomiting, abdominal bloating Metabolic: lactic acidosis Other: unpleasant metallic taste, decreased vitamin B 12 level. Urine ketones: false-positive results Drug-herbs. Glucosamine: decreased glycemic control Chromium, coenzyme Q10, fenugreek: additive hypoglycemic effects Drug-behaviors.
These factors may affect how you should take this medication. If you have severe kidney disease you are at higher risk of developing lactic acidosis. Since alcohol may increase the risk of lactic acidosis, do not drink a lot of alcohol over the short- or long-term while taking this medication. If you experience symptoms of lactic acidosis e. This medication is not recommended for people with severely reduced liver function. If you have moderately reduced liver function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Low blood sugar could occur when not enough food is eaten, especially when strenuous exercise is undertaken at the same time or when large amounts of alcohol have been consumed. You will be restarted on this medication once you are eating and drinking and your kidney function has been tested and is normal. Talk to your doctor for specific instructions.

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