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Inactivation of a neurotransmitter can be by re-uptake into the neuron it was released from, or by the action of enzymes in the synaptic cleft. NB While the exact involvement of a particular neurotransmitter in a particular CNS disorder is unknown, a question mark denotes more uncertainty about the neurotransmitter involvement. In the peripheral nervous system, transmission of information from neuron to neuron or effector is relatively simple but in the CNS, neurons are arranged into complicated systems and pathways.
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Asystole is when the heart stops beating. There are many drugs available to treat arrhythmias and the choice of drug often depends on the type of arrhythmia. Anti-arrhythmic drugs have been classified according to their mode of action into the so-called VaughanвWilliams classification. (See Drugs used to treat arrhythmias are cardiac glycosides, О-blockers, calcium channel blockers, lidocaine and amiodarone. Hypertension is defined as persistently high systemic arterial blood pressure above The VaughanвWilliams classification is of academic interest.
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It does not cross the bloodвbrain barrier easily and therefore does not have the central nervous system effects of other opiates.
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