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We will present novel methodological approaches, commonly used in other disciplines, that could be used to improve inference from MDR-TB treatment cohorts and identify the data gaps and challenges that must be overcome to implement them. Slides from this webinar can be found here. The slides used can be found here. This presentation outlined the trials necessary to determine the efficacy of new TB drugs and regimens, the design differences between a single drug and a high impact regimen, and the pathway to FDA approval. The presentations for each of these discussions can be found below. Presentation slides on Sponsor Challenges available here. Presentation slides on Challenges in Trial Implementation available here. Presentation slides on Patient Recruitment, Enrollment, and Retention available here. Presentation slides on Regulatory Requirements available here. Lorenzo Guglielmetti presented a webinar on the current evidence and practices for the combined use of delamanid and bedaquiline for the treatment of MDR-TB.

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