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Idiopathic Parkinsonвs disease occurs due to degeneration of dopamine neurons with no obvious cause. There may be a genetic susceptibility, but no causal gene has been found, although mutation of the so-called Parkin gene is associated with early-onset Parkinsonism. Post-encephalitic Parkinsonism followed an epidemic of viral encephalitis between Drug-induced Parkinsonism can occur as an adverse effect to drugs used to treat psychotic disorders.
In the early paralysis. The cause was found to be a contaminant called methylphenyltetrahydropyridine (MPTP), which causes severe degeneration of the nigrostriatal tract. This led to the suggestion that idiopathic Parkinsonвs disease may be caused by some, as yet, unidentified neurotoxin.
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This medication can cause changes in your menstruation by promoting ovulation, which can be fatal.
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Iodine-containing drugs in general, including contrast agents can cause hypothyroidism in susceptible patients.
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This arrangement makes diffusion of lipid-soluble drugs into the brain difficult and diffusion of water-soluble drugs almost impossible.
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